Fasken Martineau was retained by various contract research organizations (CROs) who received notices from Revenu Quebec for compensatory allowances granted to volunteers who participated in clinical trials. The notices retroactively nullified tax credits for R&D and salaries paid by Revenu Quebec to the CROs. A multidisciplinary team was set up to challenge the notices. Following our efforts, Revenu Quebec modified its tax law and annulled the notices sent to the CROs. Additional CROs have since received similar notices from the Canada Revenue Agency. We are currently contesting these notices as well as notices of assessment forwarded by the Revenu Quebec to volunteers that participated in clinical trials.